Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain: NCT04144972

Chronic pain affects 1 in 4 US adults, and many cases are resistant to almost any treatment. Deep brain stimulation (DBS) holds promise as a new option for patients suffering from treatment-resistant chronic pain, but traditional approaches target only brain regions involved in one aspect of the pain experience and provide continuous 24/7 brain stimulation which may lose effect over time. By developing new technology that targets multiple, complimentary brain regions in an adaptive fashion, the investigators will test a new therapy for chronic pain that has potential for better, more enduring analgesia.

Read More: https://clinicaltrials.ucsf.edu/trial/NCT04144972

Trial Link: https://clinicaltrials.gov/study/NCT04144972

If you have any questions, please reach out via email to chronicpain@ucsf.edu

Transcranial Magnetic Stimulation for Chronic Neuropathic Pain: NCT05593237

Emerging evidence suggests that the transition from acute to chronic neuropathic pain is associated with reorganization of central brain circuits involved in pain processing. Repetitive transcranial magnetic stimulation (rTMS) is a promising alternative treatment that uses focused magnetic pulses to non-invasively modulate brain activity, a strategy that can potentially circumvent the adverse effects of available treatments for pain.

Read More: https://clinicaltrials.ucsf.edu/trial/NCT05593237

Trial Link: https://clinicaltrials.gov/study/NCT05593237

If you have any questions, please reach out via email to chronicpain@ucsf.edu